| NIOSOMES: AN ULTIMATE NOVEL DRUG DELIVERY SYSTEM
|Drug targeting can be defined as the ability to direct a therapeutic agent specifically to desired site of action with little or no interaction with non target tissue. The number of carriers was utilized to carry drug at the target organ/tissue, which include immunoglobulin, serum proteins, synthetic polymers, liposome, microspheres, erythrocytes, niosomes etc.|
Among different carriers liposome and niosomes are well documented drug delivery. Niosomes are non-ionic surfactant vesicles obtained on hydration of synthetic non-ionic surfactants, with or without incorporation of cholesterol or other lipids.
They are vesicular systems similar to liposome that can be used as carriers of amphiphilic and lipophilic drugs. Niosomes are promising vehicle for drug delivery and being non-ionic; it is less toxic and improves the therapeutic index of drug by restricting its action to target cells. This presented article deals with preparation methods, characterizations, advantages, and applications of niosomes.
Keywords: niosomes, Controlled drug delivery system.
|Author :- Gaurav Gaur, Prof.Vipin Kukkar,Vipin Kumar Singhal |
Department Of Quality Assurance,Seth G.L.Bihani S.D.College Of Technical Education, Sriganganagar,rajasthan,India